Section
Methods
3 pages in this section, most recently updated September 4, 2026. Each opens with a plain-English summary and cites its sources.
01 · Methods
FeaturedHow to read a GLP-1 trial: estimands, placebo-subtracted change and responder thresholds
You'll get: Two people can quote different weight numbers from the same trial, and both can be right.
Five checks before quoting a trial weight number: who was counted, what placebo did, how wide the range is, what a threshold means, what was measured.
Updated September 4, 202602 · Methods
Weight-management trials versus diabetes trials: why the same drug gets two sets of numbers
You'll get: Each GLP-1 drug was tested in people without diabetes and in people with type 2 diabetes.
Every GLP-1 drug was tested in people with and without type 2 diabetes, and the weight results differ by about a third. How to read each kind.
Updated September 4, 202603 · Methods
FeaturedMaster comparison table: 24 pivotal GLP-1 and GIP/GLP-1 trials side by side
You'll get: This page puts all 24 trials on this site in one table, with a link to each write-up.
One table for all 24 trials on this site: drug, who was studied, how many, how long, what was measured, the result, who paid, and a link to the paper.
Updated September 4, 2026